Gene description for CD63
Gene name	CD63 molecule
Gene symbol	CD63
Other names/aliases	AD1 HOP-26 ME491 MLA1 OMA81H Pltgp40 TSPAN30
Species	Homo sapiens
Experiment description of studies that identified CD63 in Breast cancer cells
1 Experiment ID 333 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Slot blot PubMed ID 20976003    Organism Homo sapiens Experiment description Selective release of microRNA species from normal and malignant mammary epithelial cells Authors Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM Journal name PLoS One Publication year 2010 Sample Breast cancer cells Sample name MCF-7 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Slot blot RT-PCR Microarray EV-TRACK -
2 Experiment ID 334 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Slot blot PubMed ID 20976003    Organism Homo sapiens Experiment description Selective release of microRNA species from normal and malignant mammary epithelial cells Authors Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM Journal name PLoS One Publication year 2010 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Slot blot RT-PCR EV-TRACK -
3 Experiment ID 335 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Slot blot PubMed ID 20976003    Organism Homo sapiens Experiment description Selective release of microRNA species from normal and malignant mammary epithelial cells Authors Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM Journal name PLoS One Publication year 2010 Sample Breast cancer cells Sample name BT-20 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Slot blot RT-PCR EV-TRACK -
4 Experiment ID 336 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Slot blot PubMed ID 20976003    Organism Homo sapiens Experiment description Selective release of microRNA species from normal and malignant mammary epithelial cells Authors Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM Journal name PLoS One Publication year 2010 Sample Breast cancer cells Sample name MCF 10A Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Slot blot RT-PCR EV-TRACK -
5 Experiment ID 575 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name BT549 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
6 Experiment ID 577 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
7 Experiment ID 578 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
8 Experiment ID 981 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Dot blot PubMed ID 25458527    Organism Homo sapiens Experiment description Benchtop isolation and characterization of functional exosomes by sequential filtration Authors Heinemann ML, Ilmer M, Silva LP, Hawke DH, Recio A, Vorontsova MA, Alt E, Vykoukal J. Journal name J Chromatogr A. Publication year 2014 Sample Breast cancer cells Sample name MDA231 Isolation/purification methods Sequential filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Dot blot EV-TRACK EV140273: EV-METRIC:0%, 33%
9 Experiment ID 982 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Dot blot PubMed ID 25458527    Organism Homo sapiens Experiment description Benchtop isolation and characterization of functional exosomes by sequential filtration Authors Heinemann ML, Ilmer M, Silva LP, Hawke DH, Recio A, Vorontsova MA, Alt E, Vykoukal J. Journal name J Chromatogr A. Publication year 2014 Sample Breast cancer cells Sample name MDA231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Dot blot EV-TRACK EV140273: EV-METRIC:0%, 33%
10 Experiment ID 1029 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry Western blotting PubMed ID 26378940    Organism Homo sapiens Experiment description Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis. Authors Clark DJ, Fondrie WE, Liao Z, Hanson PI, Fulton A, Mao L, Yang AJ. Journal name Anal Chem. Publication year 2015 Sample Breast cancer cells Sample name SKBR3B - 100 K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV150004: EV-METRIC:67%, 38%
11 Experiment ID 1030 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 26378940    Organism Homo sapiens Experiment description Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis. Authors Clark DJ, Fondrie WE, Liao Z, Hanson PI, Fulton A, Mao L, Yang AJ. Journal name Anal Chem. Publication year 2015 Sample Breast cancer cells Sample name SKBR3B - Opti pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.14 -1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV150004: EV-METRIC:67%, 38%
12 Experiment ID 886 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting Mass spectrometry PubMed ID 25102470    Organism Homo sapiens Experiment description Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro Authors Smyth TJ, Redzic JS, Graner MW, Anchordoquy TJ. Journal name Biochim Biophys Acta Publication year 2014 Sample Breast cancer cells Sample name MCF-7 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.10-1.20 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140013: EV-METRIC:56%
13 Experiment ID 2449 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting Immuno-EM PubMed ID 34465793    Organism Homo sapiens Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Authors Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K. Journal name Nat Commun Publication year 2021 Sample Breast cancer cells Sample name MCF7BoM2 - 100K pellet Isolation/purification methods Centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Immuno-EM miRNA array qPCR EV-TRACK -
14 Experiment ID 1622 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34796683    Organism Homo sapiens Experiment description High TSPAN8 expression in epithelial cancer cell-derived small extracellular vesicles promote confined diffusion and pronounced uptake Authors Wang T, Wang X, Wang H, Li L, Zhang C, Xiang R, Tan X, Li Z, Jiang C, Zheng L, Xiao L, Yue S. Journal name J Extracell Vesicles Publication year 2021 Sample Breast cancer cells Sample name T-47D Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
15 Experiment ID 1623 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34796683    Organism Homo sapiens Experiment description High TSPAN8 expression in epithelial cancer cell-derived small extracellular vesicles promote confined diffusion and pronounced uptake Authors Wang T, Wang X, Wang H, Li L, Zhang C, Xiang R, Tan X, Li Z, Jiang C, Zheng L, Xiao L, Yue S. Journal name J Extracell Vesicles Publication year 2021 Sample Breast cancer cells Sample name T-47D Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
16 Experiment ID 1937 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36193887    Organism Homo sapiens Experiment description Machine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity Authors Ramos EK, Tsai CF, Jia Y, Cao Y, Manu M, Taftaf R, Hoffmann AD, El-Shennawy L, Gritsenko MA, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Liu X, Patel P, Wray B, Zhang Y, Zhang S, Moore RJ, Mathews JV, Schipma MJ, Liu T, Tokars VL, Cristofanilli M, Shi T, Shen Y, Dashzeveg NK, Liu H. Journal name Elife Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
17 Experiment ID 1938 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36193887    Organism Homo sapiens Experiment description Machine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity Authors Ramos EK, Tsai CF, Jia Y, Cao Y, Manu M, Taftaf R, Hoffmann AD, El-Shennawy L, Gritsenko MA, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Liu X, Patel P, Wray B, Zhang Y, Zhang S, Moore RJ, Mathews JV, Schipma MJ, Liu T, Tokars VL, Cristofanilli M, Shi T, Shen Y, Dashzeveg NK, Liu H. Journal name Elife Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
18 Experiment ID 1939 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36193887    Organism Homo sapiens Experiment description Machine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity Authors Ramos EK, Tsai CF, Jia Y, Cao Y, Manu M, Taftaf R, Hoffmann AD, El-Shennawy L, Gritsenko MA, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Liu X, Patel P, Wray B, Zhang Y, Zhang S, Moore RJ, Mathews JV, Schipma MJ, Liu T, Tokars VL, Cristofanilli M, Shi T, Shen Y, Dashzeveg NK, Liu H. Journal name Elife Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
19 Experiment ID 1985 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35915084    Organism Homo sapiens Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
20 Experiment ID 1986 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35915084    Organism Homo sapiens Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
21 Experiment ID 1987 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35915084    Organism Homo sapiens Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
22 Experiment ID 1988 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35915084    Organism Homo sapiens Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
23 Experiment ID 1989 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35915084    Organism Homo sapiens Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
24 Experiment ID 1990 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35915084    Organism Homo sapiens Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
25 Experiment ID 1991 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35915084    Organism Homo sapiens Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
26 Experiment ID 1992 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35915084    Organism Homo sapiens Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
27 Experiment ID 2452 Identified molecule protein Extracellular vesicle type Apoptotic bodies MISEV Large EVs Identification method Western blotting PubMed ID 34465793    Organism Homo sapiens Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Authors Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K. Journal name Nat Commun Publication year 2021 Sample Breast cancer cells Sample name MCF7BoM2 - 2K pellet Isolation/purification methods Centrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting qPCR EV-TRACK -
28 Experiment ID 2453 Identified molecule protein Extracellular vesicle type Microvesicles MISEV Large EVs Identification method Western blotting PubMed ID 34465793    Organism Homo sapiens Experiment description Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Authors Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K. Journal name Nat Commun Publication year 2021 Sample Breast cancer cells Sample name MCF7BoM2 - 10K pellet Isolation/purification methods Centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting qPCR EV-TRACK -
29 Experiment ID 2497 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 34329193    Organism Homo sapiens Experiment description CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis Authors Zhang W, Liu H, Jiang J, Yang Y, Wang W, Jia Z. Journal name Aging Publication year 2021 Sample Breast cancer cells Sample name BT-549 Isolation/purification methods Total Exosome Isolation Reagent Flotation density - Molecules identified in the study Protein miRNA circRNA Methods used in the study Western blotting qRT-PCR EV-TRACK -
30 Experiment ID 2498 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 34329193    Organism Homo sapiens Experiment description CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis Authors Zhang W, Liu H, Jiang J, Yang Y, Wang W, Jia Z. Journal name Aging Publication year 2021 Sample Breast cancer cells Sample name BT-549-H (high metastatic potential) Isolation/purification methods Total Exosome Isolation Reagent Flotation density - Molecules identified in the study Protein miRNA circRNA Methods used in the study Western blotting qRT-PCR EV-TRACK -
31 Experiment ID 2863 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
32 Experiment ID 2864 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
33 Experiment ID 2867 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry EV-TRACK -
34 Experiment ID 2868 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
35 Experiment ID 2869 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
36 Experiment ID 2870 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry EV-TRACK -
37 Experiment ID 2873 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
38 Experiment ID 2874 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
39 Experiment ID 2875 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
40 Experiment ID 2876 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
41 Experiment ID 2885 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name BALB/c implanted with MDA-MB-231-luci (+) Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
42 Experiment ID 2886 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name MDA-MB-231-luci (+) Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
43 Experiment ID 2888 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name BALB/c implanted with MDA-MB-231-WT Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
44 Experiment ID 2889 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name BALB/c implanted with MDA-MB-231-ETA KD Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
45 Experiment ID 3008 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 30089911    Organism Homo sapiens Experiment description Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Authors Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. Journal name Nature Publication year 2018 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
46 Experiment ID 3010 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 30089911    Organism Homo sapiens Experiment description Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Authors Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. Journal name Nature Publication year 2018 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
47 Experiment ID 3223 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32111843    Organism Homo sapiens Experiment description A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA Authors de Jong OG, Murphy DE, Mäger I, Willms E, Garcia-Guerra A, Gitz-Francois JJ, Lefferts J, Gupta D, Steenbeek SC, van Rheenen J, El Andaloussi S, Schiffelers RM, Wood MJA, Vader P. Journal name Nat Commun Publication year 2020 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Tangential flow filtration Filtration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
48 Experiment ID 3514 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Thermophoretic aptasensor (TAS) PubMed ID 30948809    Organism Homo sapiens Experiment description Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Authors Liu C, Zhao J, Tian F, Cai L, Zhang W, Feng Q, Chang J, Wan F, Yang Y, Dai B, Cong Y, Ding B, Sun J, Tan W. Journal name Nat Biomed Eng Publication year 2019 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Thermophoretic aptasensor (TAS) EV-TRACK -
49 Experiment ID 1963 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35915084    Organism Homo sapiens Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry Immuno-EM Flow cytometry ELISA EV-TRACK -
50 Experiment ID 1568 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Immunofluorescence PubMed ID 33738083    Organism Homo sapiens Experiment description Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases Authors Lim GT, You DG, Han HS, Lee H, Shin S, Oh BH, Kumar EKP, Um W, Kim CH, Han S, Lee S, Lim S, Yoon HY, Kim K, Kwon IC, Jo DG, Cho YW, Park JH Journal name J Extracell Vesicles Publication year 2021 Sample Breast cancer cells Sample name MDA‐MB‐231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immunofluorescence Flow cytomtery EV-TRACK -
51 Experiment ID 1569 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Immunofluorescence PubMed ID 33738083    Organism Homo sapiens Experiment description Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases Authors Lim GT, You DG, Han HS, Lee H, Shin S, Oh BH, Kumar EKP, Um W, Kim CH, Han S, Lee S, Lim S, Yoon HY, Kim K, Kwon IC, Jo DG, Cho YW, Park JH Journal name J Extracell Vesicles Publication year 2021 Sample Breast cancer cells Sample name MDA‐MB‐231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immunofluorescence Flow cytomtery EV-TRACK -
52 Experiment ID 1568 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Flow cytometry PubMed ID 33738083    Organism Homo sapiens Experiment description Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases Authors Lim GT, You DG, Han HS, Lee H, Shin S, Oh BH, Kumar EKP, Um W, Kim CH, Han S, Lee S, Lim S, Yoon HY, Kim K, Kwon IC, Jo DG, Cho YW, Park JH Journal name J Extracell Vesicles Publication year 2021 Sample Breast cancer cells Sample name MDA‐MB‐231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immunofluorescence Flow cytomtery EV-TRACK -
53 Experiment ID 1569 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Flow cytometry PubMed ID 33738083    Organism Homo sapiens Experiment description Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases Authors Lim GT, You DG, Han HS, Lee H, Shin S, Oh BH, Kumar EKP, Um W, Kim CH, Han S, Lee S, Lim S, Yoon HY, Kim K, Kwon IC, Jo DG, Cho YW, Park JH Journal name J Extracell Vesicles Publication year 2021 Sample Breast cancer cells Sample name MDA‐MB‐231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immunofluorescence Flow cytomtery EV-TRACK -
54 Experiment ID 1664 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Flow cytometry PubMed ID 34108659    Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. Journal name Nat Cell Biol Publication year 2021 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry EV-TRACK -
55 Experiment ID 1666 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Flow cytometry PubMed ID 34108659    Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. Journal name Nat Cell Biol Publication year 2021 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry EV-TRACK -